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NINLARO 1Point® overview

NINLARO 1Point is designed to assist patients with coverage, access, and staying on therapy

NINLARO 1Point is a comprehensive support program that offers an array of access and coverage services for patients taking NINLARO® (ixazomib).*

Our dedicated case management team can deliver personalized services that help your patients taking NINLARO and providers navigate coverage requirements for NINLARO, streamline product access, and connect to helpful resources.

Support services include:

  • Benefit verification and prior authorization assistance
  • Assistance with appealing a payer denial
  • NINLARO Co-pay Assistance Program enrollment for eligible, commercially insured patients
    -  Enrollment can be completed by patients, physicians, and pharmacists at
  • Specialty pharmacy routing and coordination
  • Connection to support services, information about other treatment related support programs and services that patients may be eligible for
  • NINLARO RapidStart Program for eligible patients with insurance-related coverage determination delays
  • Patient Assistance Program application
  • *Eligibility requirements and program terms and conditions apply.
  • NINLARO 1Point does not file claims or appeal claims for callers. It cannot guarantee success in overturning payer denials.



Your patient's dedicated NINLARO 1Point® case manager will assist with the benefit verification process by:

  • Researching current, payer-specific coverage guidelines for NINLARO® (ixazomib) on behalf of your patient
  • Using information provided during the enrollment process to identify payer policies requiring verification
  • Notifying your office of verification outcome/status within 2 business days
  • Providing your office with a summary of benefits outlining patient's cost share, exclusions, prior authorization requirements, and other details
  • Determining specialty pharmacies in your patient's payer network or routing your prescription to your preferred specialty pharmacy

Prior authorization assistance with NINLARO 1Point by:

  • Supplying your office with a summary of payer's prior authorization process and submission requirements
  • Recording prior authorization expiration date and sending a renewal reminder to your office and patient 30 days prior
  • Routing prescription to specialty pharmacy in the payer's network
  • Contacting specialty pharmacy to monitor and record prior authorization status
  • *Eligibility requirements and program terms and conditions apply.

NINLARO 1Point® enrollment


Complete the Enrollment Form

  • You and your patient will complete the NINLARO 1Point Enrollment Form. Please ensure your patient also provides a copy of their insurance card, if they have one. Your office will then submit the patient's insurance information along with a copy of the insurance card and prescription to NINLARO 1Point
  • *Eligibility requirements and program terms and conditions apply.

NINLARO 1Point® assistance


  • *Eligibility requirements and program terms and conditions apply.

Has an insurance delay

NINLARO RapidStart Program

The RapidStart Program can provide a 28-day (1-cycle) supply of NINLARO® (ixazomib) at no cost to patients who may experience a delay in insurance coverage determination of at least 7 business days. Terms and conditions apply.†‡

The RapidStart Program provides a 28-day (1-cycle) supply of treatment of NINLARO at no charge for eligible patients new to NINLARO experiencing a delay in insurance coverage determination of at least 7 business days. There is no purchase obligation by virtue of a patient's participation in the RapidStart Program. Patients must have an on-label prescription for NINLARO consistent with the FDA-approved label for NINLARO and be enrolled in the NINLARO 1Point Program to qualify. Free product for the RapidStart Program will only be available through the RapidStart Program non-commercial specialty pharmacy. A delay in coverage determination of at least 7 business days is required for patients to be eligible for the RapidStart Program. The program may not be combined with any other offer and is not available to patients whose insurers have made a final determination to deny the patient coverage for NINLARO. Takeda reserves the right to change or end the program at any time. Benefits provided under the program are not transferable.

Eligibility is determined by monitoring of prescription status and coordination with in-office dispensing providers.

How to enroll a new NINLARO patient in the RapidStart Program

  • In order to receive the RapidStart Program supply, your practice must submit a completed NINLARO 1Point Enrollment Form and an on-label prescription for NINLARO to NINLARO 1Point on behalf of your eligible patients
  • Eligibility criteria require that the:
    • Patient has a clinically appropriate diagnosis for NINLARO as per the FDA-approved label
    • Patient must be new to NINLARO therapy
    • Patient must have experienced a delay in insurance coverage determination of at least 7 business days
  • Patients who have Medicare Part D or commercial insurance coverage may be eligible

How the RapidStart Program manages coverage determination delays

  • NINLARO 1Point must have received a completed enrollment form signed by the physician and patient
  • The RapidStart Program will confirm with the office and the payer that all required information has been submitted to the payer
  • If after 7 business days the RapidStart Program confirms that the payer has not made a coverage determination, the RapidStart Program supply will be sent to the patient

No insurance or underinsured

Patient Assistance Program

The Patient Assistance Program provides assistance to patients who either do not have insurance or are functionally underinsured. The program offers monthly supplies of NINLARO® (ixazomib) at no cost to patients who meet certain eligibility requirements.

How to apply

In order to apply, your patient must:

Complete the Patient Assistance Program Application. It is important to note that you and your patient must sign this application.
Have a valid prescription for NINLARO.
Have 1 of the documents listed in the Patient Assistance Program Application that is required for household income verification.

If your patient is approved for this program, both of you will be notified, and a 1-month supply of NINLARO will be mailed to your patient. Each month, you will need to confirm that your patient still needs NINLARO.

Qualifying patients may be enrolled for up to 1 year.

Download patient assitance program application

NINLARO 1Point® distribution network


Specialty pharmacies

  • Payer's or provider's preferred specialty pharmacy
  • Any specialty pharmacy within the NINLARO network

In-office dispensing

  • To arrange in-office dispensing, please contact your distributor/wholesaler or NINLARO 1Point directly
    Phone: 1-844-N1POINT (1-844-617-6468); select option 5; Mon-Fri, 8 AM-8 PM ET
Download a list of specialty PHARMACIES within the NINLARO network
  • *Eligibility requirements and program terms and conditions apply.

additional resources


Our NINLARO 1Point case managers can help your patients find the information and day-to-day or long-term support they need, including:

  • Access to resources about living with cancer: support and information, local and national advocacy groups
  • Referral to travel assistance (eg, to appointments)
  • Information about organizations providing legal services
  • Referral to counseling and support programs
  • Referral to emotional support resources
  • *Eligibility requirements and program terms and conditions apply.


Letter of appeal

In the event that a payer denies a claim for NINLARO, you and your patient may want to appeal the decision. It is important to follow the payer's appeal guidelines and time frames. The following sample letter is intended as a general guide for requesting reconsideration for denied claims.

NINLARO 1Point does not file claims or appeal claims for callers. It cannot guarantee success in overturning payer denials.

Download sample letter of appeal

Letter of medical necessity

Some payers may require the healthcare provider to submit a letter or statement of medical necessity for NINLARO. The following sample letter is intended as a general guide for submitting information to payers to substantiate medical necessity.

Download sample letter of medical necessity

Empower Program


Empower is a no cost program that provides personalized education and support to patients who are taking NINLARO® (ixazomib) as part of their treatment plan.

When eligible patients join Empower, they will have access to*:

  • The support of an Adherence Clinical Educator (ACE), with a background in oncology nursing
  • A personalized plan to help your patients manage treatment and become an empowered participant in their care
  • Ongoing support from an ACE, including regular communications based on your patient’s personal preferences
  • Education and support resources, including tips on working with their healthcare team
  • *Restrictions apply. Your patient can opt out of the program at any time.


Contact Ninlaro 1point

Call 1-844-617-6468 AND

Co-pay program

NINLARO® (ixazomib) Co-Pay Assistance Program for your commercially insured patients

NINLARO® (ixazomib) - Progression-Free Survival

If your patients have commercial insurance and are concerned about their ability to pay for NINLARO, they may qualify for the NINLARO Co-pay Assistance Program. See eligibility requirements.†‡

Eligibility Requirements: This offer cannot be used if your patient is a beneficiary of, or any part of their prescription is covered by: 1) any federal or state healthcare program (Medicare, Medicaid, TRICARE, VA, DoD, etc.), including state or territory pharmaceutical assistance programs, 2) the Medicare Prescription Drug Program (Part D), or if they are currently in the coverage gap, Medicare Advantage Plans, Medicaid Managed Care or Alternative Benefit Plans under the Affordable Care Act, or Medigap, or 3) insurance that is paying the entire cost of the prescription. Patients must be at least 18 years old.

Terms & Conditions: Your patient must meet Eligibility Requirements. They agree to report their use of this offer to any third party that reimburses them or pays for any part or the prescription price. Use of this offer is confirmation that they are permitted, under the terms and conditions of the health benefit plan(s) covering their prescriptions, to take advantage of co-pay coverage programs. Your patient additionally agrees that they will not submit the cost of any portion of the product dispenses pursuant to this offer to a federal or state healthcare program for purposes of counting it toward out-of-pocket expenses, and to notify NINLARO 1Point if they become eligible for a federal, state, Veterans Affairs, or similar healthcare program. This savings program covers out-of-pocket expenses greater than $25 per monthly prescription. Maximum $25,000 annually. Your patients’ co-pay card can be renewed every 12 months. This offer is not valid with any other program, discount, or incentive involving NINLARO. This offer may be rescinded, revoked or amended without notice. No reproductions. This offer is void where prohibited by law, taxed, or restricted. Limit one offer per purchase. Cash value of 1/100 of 1¢. For questions about this offer, please contact the NINLARO Co-Pay Assistance Program, a service of NINLARO 1Point, at 1-844-N1POINT (1-844-617-6468), Option 2, Monday-Friday, 8AM-8PM ET.

How TO enroll

Visit to see enrollment options. Use this site to reenroll, activate a card, or request a replacement card. Patients may also enroll in this program by contacting NINLARO 1Point® at 1-844-617-6468, as well as through you or their designated specialty pharmacy.

  • *Eligibility requirements and program terms and conditions apply.

Tools and resources for NINLARO® (ixazomib)

Healthcare professionals

NINLARO dosing guide
A comprehensive look at NINLARO dosing, including dose modifications, instructions for safe handling, and adverse events data.

Adverse Event Management With NINLARO
A snapshot of the NINLARO safety profile with information on managing symptoms and dose modifications.

For your patients

Treatment Calendar
Have your patients track their individual treatment schedule by filling out this calendar.

Lab Test Tracker
A tool to help your patients keep a personal record of their lab tests and better understand their results.

1Point Patient Support Program

NINLARO 1Point Summary
See a comprehensive overview of NINLARO 1Point patient support services.

NINLARO 1Point Enrollment Form
An interactive PDF to help your patients get started with NINLARO 1Point.